“Now we have a better understanding of how stress is generated,” says Tomas Hökfelt of the Karolinska Institutet and guest professor at the MedUni Vienna. This could result in a further development where secretagogin is deployed as a tool to treat stress, perhaps in people suffering from mental illness such as depression, burn out or posttraumatic stress disorder, but also in cases of chronic stress brought on by pain. If a rapid recovery phase follows a period of stress, body and mind are restored to “normal working”, which is associated with a suppression of the release of circulating stress hormones.